{"id":3215,"date":"2025-02-19T18:37:35","date_gmt":"2025-02-19T18:37:35","guid":{"rendered":"https:\/\/lightseagreen-goshawk-333311.hostingersite.com\/product\/mephedrone\/"},"modified":"2025-06-21T18:58:47","modified_gmt":"2025-06-21T18:58:47","slug":"mephedrone","status":"publish","type":"product","link":"https:\/\/myk2spicestore.com\/fr\/produit\/mephedrone\/","title":{"rendered":"Mephedrone"},"content":{"rendered":"<div id=\"wb_Text4\">The base is a yellowish liquid at ambient temperature.<\/div>\n<div>\n<p>Mephedrone hydrochloride salt is a white or lightly coloured powder.<\/p>\n<p>4-Methylmethcathinone (also known as 4-MMC, M-CAT, drone, meow meow, and mephedrone) is a entactogen-stimulant\u00a0substance\u00a0of the cathinone class.<\/p>\n<\/div>\n<div>\n<p>Mephedrone belongs to a group known as the substituted cathinone, which are derivatives of the active ingredient in the khat plant (Catha edulluis).<\/p>\n<p>Meph was first synthesized in 1929, but did not become widely known until it was rediscovered in 2003.<\/p>\n<\/div>\n<div>By 2007, it was reported to be available for sale on the internet.<\/div>\n<div>Also, by 2008 law enforcement agencies had become aware of the compound.<\/div>\n<div>\n<p>Furthermore, by 2010 it had been reported in most of Europe, becoming particularly prevalent in the United Kingdom.<\/p>\n<p>It comes in the form of tablets or a powder, which users can swallow, snort, inject or insert\u00a0rectally.<\/p>\n<\/div>\n<div>It produces effects which are somewhat similar to those of MDMA, amphetamine, and cocaine.<\/div>\n<div>\n<p>It is reported to produce a mixture of classic stimulant and entactogenic effects effects reminiscent of cocaine and MDMA.<\/p>\n<\/div>\n<div>\n<h5>Pharmacology of Mephedrone<\/h5>\n<p>Given its chemical structure, it is likely to act as a releasing agent and a reuptake inhibitor for monoamine neurotransmitters.<\/p>\n<\/div>\n<div>\n<p>Such monoamine neurotransmitters are dopamine, serotonin and noradrenaline.<\/p>\n<p>Several articles published near the end of 2011 examined the effects of mephedrone in the brains of rats.<\/p>\n<\/div>\n<div>Dopamine and serotonin were collected using microdialysis, and increases in dopamine and serotonin were measured.<\/div>\n<div>\n<p>the administration caused about a 500% increase in dopamine, and about a 950% increase in serotonin. They reached their peak concentrations at 40 minutes and 20 minutes and returned to baseline by 120 minutes after injection.<\/p>\n<p>Analysis of the ratio for dopamine and serotonin indicated mephedrone was preferentially a serotonin releaser. Additionally, half-lives for the decrease in dopamine and serotonin were found to have decay rates of 24.5 minutes and 25.5 minutes<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>The base is a yellowish liquid at ambient temperature. Mephedrone hydrochloride salt is a white or lightly coloured powder. 4-Methylmethcathinone (also known as 4-MMC, M-CAT, drone, meow meow, and mephedrone) is a entactogen-stimulant\u00a0substance\u00a0of the cathinone class. Mephedrone belongs to a group known as the substituted cathinone, which are derivatives of the active ingredient in the [&hellip;]<\/p>","protected":false},"featured_media":3214,"comment_status":"open","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[15],"product_tag":[],"class_list":{"0":"post-3215","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-k2-spice-powder","7":"desktop-align-left","8":"tablet-align-left","9":"mobile-align-left","11":"first","12":"instock","13":"shipping-taxable","14":"purchasable","15":"product-type-variable"},"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/myk2spicestore.com\/fr\/wp-json\/wp\/v2\/product\/3215","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/myk2spicestore.com\/fr\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/myk2spicestore.com\/fr\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/myk2spicestore.com\/fr\/wp-json\/wp\/v2\/comments?post=3215"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/myk2spicestore.com\/fr\/wp-json\/wp\/v2\/media\/3214"}],"wp:attachment":[{"href":"https:\/\/myk2spicestore.com\/fr\/wp-json\/wp\/v2\/media?parent=3215"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/myk2spicestore.com\/fr\/wp-json\/wp\/v2\/product_brand?post=3215"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/myk2spicestore.com\/fr\/wp-json\/wp\/v2\/product_cat?post=3215"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/myk2spicestore.com\/fr\/wp-json\/wp\/v2\/product_tag?post=3215"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}